4 edition of Sialic acids, chemistry, metabolism, and function found in the catalog.
Includes bibliographies and index.
|Statement||edited by R. Schauer.|
|Series||Cell biology monographs ;, v. 10|
|Contributions||Schauer, R. 1936-|
|LC Classifications||QP801.S47 S55 1982|
|The Physical Object|
|Pagination||xvii, 344 p. ;|
|Number of Pages||344|
|LC Control Number||82019326|
AbstractThe role of sialic acid (SA) in the pathogenesis of atherosclerosis and as a predictor of cardiovascular events has attracted much attention in recent years. However, most studies investigating the role of total and lipid-bound sialic acids (TSA and LSA) in the pathogenesis of atherosclerosis lack information on the reason for the elevated SA Cited by: Hayes, B., and Varki, A. O-Acetylation and de-O-acetylation of sialic acids. Sialic acid esterases of diverse evolutionary origins have serine active sites and essential arginine residues. J Biol Chem.
Keywords: sialic acid diversity, sialic acid functions, sialic acid future aspects, sialic acid metabolism, sialic acid occurrence Introduction research groups, ®rst at the university in Bochum, and since in Kiel, on sialic acids, and will discuss the future Alfred Gottschalk, who wrote the ®rst book on sialic acids mainstreams and. Enter search terms. Keep search filters New search. Advanced search.
John L. Tymoczko. John L. Tymoczko is Towsley Professor of Biology at Carleton College, where he has taught since He currently teaches Biochemistry, the Metabolic Basis of Human Disease, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry and co-teaches an introductory course, Energy Flow in Biological. Simple Lipids B. Waxes Esters of fatty acids with higher molecular weight monohydric alcohols – Cetyl Alcohol (C16H33OH) • Not important for human metabolism • E.g. Bee-wax, Lanolin from lamb’s wool • Waxes has water repellant property. .
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In chemistry book emphasis is given to various and function book methods used in the isolation and analysis of sialic acids. New approaches to the synthesis of free and bound sialic acids are described and function book the vast field of occurrence and metabolism of these substances is reviewed.
Sialidoses are dealt with in one of the chapters, because sialidases have been. : Sialic Acids: "Chemistry, Metabolism, and Function" (Cell Biology Monographs) (): Roland Schauer: Books. Genre/Form: Aufsatzsammlung: Additional Physical Format: Online version: Sialic acids, chemistry, metabolism, and function.
Wien ; New York: Springer-Verlag, Sialic acids: Chemistry, metabolism and function (Cell biology monographs, vol. metabolism edited by R. Schauer, Springer-Verlag, DM /US $ (xvii + ) ISBN 3 7 (German edition) ISBN 0 7 (English edition)Cited by: from book Sialic Acids: Chemistry, Metabolism, and Function (pp) Isolation and Purification of Sialic Acids Chapter January with Reads.
Get this from a library. Sialic Acids: Chemistry, Metabolism, and Function. [Roland Schauer] -- Rapid progress in the field of sialic acids has made it desirable to collect the new data about these unique sugars and to continue the series of books on. Abstract. The wide occurrence of sialic acids in nature is an indication of their great biological importance.
As is described in other chapters in this book, the identification of the chemistry acids was pioneered in several laboratories, while the biosynthetic mechanism of sialic acid formation was elucidated essentially by the work of R oseman’s and W arren’s groups in the United States Cited by: Essentials of Glycobiology.
This book explains the following topics: General Principles, Saccharide Structure and Nomenclature, Evolution of Glycan Diversity, Protein Glycan Interactions, Exploring the Biological Roles of Glycans, Biosynthesis, Metabolism, and Function, N Glycans, Proteoglycans and Glycosaminoglycans, Nuclear and Cytoplasmic Glycosylation.
Reuter, S. Stoll, J.P. Kamerling, J.F. Vliegenthart and R. Schauer () Sialic acids on erythrocytes and in blood plasma of mammals, in: Sialic Acids - Proceedings of the Japanese-German Symposium on Sialic Acids (R.
Schauer and T. Yamakawa, eds.) pp 88–89, Verlag Wissenschaft and Bildung, by: Sialic acids exert their function in biology through multiple mechanisms as they are directly and indirectly involved in numerous events at both the molecular and cellular level [2, 3].
Several of. This chapter describes the sialic acid family of monosaccharides, with respect to their biosynthesis, structural diversity, and linkage to the underlying glycan chain.
Also mentioned are the general principles behind different methods for their study. The biological and pathophysiological roles of sialic acids are briefly considered, particularly the functional. The chemistry and biology of sialic acids and related substances.
Cambridge University Press, Cambridge. Gottschalk A., ed. The chemistry and biology of sialic acids and related substances. Sialic acids, chemistry, metabolism, and function. Springer-Verlag, New York. Ginsburg V. and Robbins P., eds.
Books and Monograph Author: Ajit Varki, Richard D Cummings, Jeffrey D Esko, Hudson H Freeze, Pamela Stanley, Carolyn R Bertozzi.
Kabat cited Yamakawa's work in his book as follows, ‘The final product gave a “clear colloidal solution” in water: reducing sugar (as galactose) 53–56%, hexosamine (as glucosamine HCl) %, N %; about 2 µg inhibited hemagglutinating doses of anti-A or anti-B.
Yamakawa and Iida have reported that globoside contains fatty acids and Cited by: 4. Gangliosides are negatively charged glycosphingolipids that consist of a hydro- phobic ceramide and a hydrophilic oligosaccharide chain bearing one or more sialic acid residues in addition to a number of sugars, namely glucose, galactose, N-acetylglucosamine and N-acetylgalactosamine (Wiegandt, ).Ceramide is an N-acylsphingosine in which the acyl residue is usually a.
Sialic acids, a subset of nine carbon acidic sugars, often exist as the terminal sugars of glycans on either glycoproteins or glycolipids on the cell surface. Sialic acids play important roles in many physiological and pathological processes via carbohydrate-protein interactions, including cell–cell communication, bacterial and viral infections.
In particular, hypersialylation in Author: Xiaoman Zhou, Ganglong Yang, Feng Guan. Gottschalk (Ed.), The Chemistry and Biology of Sialic Acids and Related Substances, Cambridge University Press ()Cited by: Unnatural analogues of sialic acid can be delivered to mammalian cell surfaces through the metabolic transformation of unnatural N-acetylmannosamine (ManNAc) derivatives.
In previous studies, mannosamine analogues bearing simple N-acyl groups up to five carbon atoms in length were recognized as substrates by the biosynthetic machinery and transformed into cell surface Cited by: We developed a copper(I)-catalyzed stereodivergent anomeric propargylation of unprotected aldoses as a facile synthetic pathway to a broad variety of sialic acid derivatives.
The soft allenylcopper(I) species, catalytically generated from stable allenylboronic acid pinacolate (2), is unusually inert to protonolysis by the multiple hydroxy groups of the substrates and thereby.
Metabolism of sialic acids Two projects on the metabolism of Sia focussed on sialidase and Neu5Ac hydroxylase. With sialidases we were mainly interested in their substrate specificities, especially with differently O-acetylated Sia.
This was also of practical importance, enabling the localization of O-acetyl groups in glycan-bound Sia. Neuraminidase enzymes are glycoside hydrolase enzymes that cleave (cut) the glycosidic linkages of neuraminic inidase enzymes are a large family, found in a range of organisms.
The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used.
acid [as´id] 1. sour. 2. a substance that yields hydrogen ions in solution and from which hydrogen may be displaced by a metal to form a salt. For the various acids, see under the specific name, such as acetic acid.
All acids react with bases to form salts and water (neutralization). Other properties of acids include a sour taste and the ability to.Sialic acids are a family of sugars, N‐acetylneuraminic acid (NeuAc) or N‐glycolylneuraminic acid (NeuGc), with more than 20 derivatives, which differs only in the acyl substitution of the C‐5 amino group .
Most of the other sialic acids contain one or more O‐acetyl substitutions of the hydroxyl groups at C‐4, C‐7, or C‐ by: Abstract.
The sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) differ by a single oxygen atom and are widely found at the terminal position of glycans on vertebrate cell animals capable of synthesizing Neu5Gc, most tissues and cell types express both sialic acids, in proportions that vary Cited by: